Description
HSP60 Antibody [HSPD1/875] | 33-397 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Monkey, Mouse, Rat, Hamster, Guinea Pig, Chicken
Homology: N/A
Immunogen: Recombinant human HSPD1 protein was used as the immunogen for the HSP60 antibody.
Research Area: Signal Transduction
Tested Application: Flow, IF
Application: Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Immunofluorescence: 0.5-1 ug/ml
Optimal dilution of the HSP60 antibody should be determined by the researcher.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein G affinity chromatography
Clonality: Monoclonal
Clone: HSPD1/875
Isotype: IgG1, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
Alternate Name: 60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, HSPD1, HSP60
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60) . A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps) , more appropriately called as stress response proteins (srps) . HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.