400

HSP70 Antibody, Clone 1H11, Biotin

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SKU:
400-SMC-249D-BI-GEN
Availability:
IN STOCK
£1,390.00

Description

Mouse Anti-Human Cell Membrane HSP70 Monoclonal IgG1

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Additional Information

Size:
100 µg
Other Name:
HSP70 Antibody: Biotin
Target:
HSP70
Conjugate:
Biotin
Research Area:
Cell Signaling, Protein Trafficking, Chaperone Proteins, Cancer, Tumor Biomarkers, Heat Shock
Alternative Name(s):
HSP70 1 Antibody, HSP70 2 Antibody, HSP70.1 Antibody, HSP72 Antibody, HSPA1 Antibody, HSPA1A Antibody, HSPA1B Antibody
Product Type:
Monoclonal Antibody
Clone Number:
1H11
Immunogen:
Human native HSP70 protein
Immunogen Species:
Human
Applications:
WB, ICC/IF, FCM, FACS
Host:
Mouse
Isotype:
IgG1
Species Reactivity:
Human, Mouse, Rat, Bovine, Pig
Antibody Dilution:
WB (1:1000), ICC/IF (1:100), FACS (1:250); optimal dilutions for assays should be determined by the user.
Purification:
Protein G Purified
Storage Buffer:
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration:
0.5 mg/ml
Specificity:
Conformation-specific antibody for membrane-bound HSP70. Binds to cell surface HSP70 without permeabilization of cell membrane in tumor cell lines. Does not bind to intracellular HSP70 at low concentrations. Cross-reacts with HSC70. Detects a ~70 kDa
Storage:
-20ºC
Shipping:
Blue Ice or 4ºC
Certificate of Analysis:
A 1:250 dilution of SMC-249 was sufficient for detection of cell surface HSP70 in HCT116 cells using Fluorescence-activated cell sorting, applied in flow cytometry, with FITC as the fluorescent probe.
Cellular Localization:
Cell membrane
Accession Number:
NP_005336.3
Gene ID:
3303
Swiss-Prot:
P0DMV8/P0DMV9
Field of Use:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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