749

Human CD155/PVR protein, His tag (Animal-Free) | PRP2024

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SKU:
749-PRP2024
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€405.00 - €1,296.00

Description

Human CD155/PVR protein, His tag (Animal-Free) | PRP2024 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines (Animal-Free)

Sequence: Amino acid sequence derived from human CD155 (NP_006496.3) (Met1-Asn343) was expressed with a 6 His tag at the C-terminus.

Activity: N/A

protein Lenght: The recombinant human CD155 consists of 329 amino acids and predicts a molecular mass of 35.9 KD. It migrates as an approximately 53-70 KD band in SDS-PAGE under reducing conditions due to glycosylation.

Preparation: HEK293 Cells

Purity: >95% as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS, pH 7.4.

Kit Component: N/A

Features & Benefits : Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 35.9 KD

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human CD155/PVR protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human CD155/PVR protein, His tag (Animal-Free) should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.21% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: CD155 is a transmembrane adhesion protein that belongs to the immunoglobulin superfamily. It possesses three immunoglobulin-like domains, a transmembrane domain, and the intracellular domain. CD155 is encoded by eight exons and differential mRNA splicing results in four isoforms named PVRα, PVRβ, PVRγ, and PVRδ. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.

Alternative Names: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Search Names: Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Tag: CD155/PVR

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