Human CellExp™ BCMA / TNFRSF17, Fc Tag, Cynomolgus / Rhesus macaque Recombinant | P1202

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

P1202 | Human CellExp BCMA / TNFRSF17 Fc Tag Cynomolgus / Rhesus macaque Recombinant DataSheet

Biomolecule/Target: TNFRSF17

Synonyms: TNFRSF17, CD269, BCM, BCMA

Alternates names: Proepithelin, PEPI, PC Cell-derived Growth Factor.

Taglines: A member of the TNF receptor superfamily

NCBI Gene ID #: 10090

NCBI Gene Symbol: GRN

Gene Source: Cynomolgus/Rhesus macaque

Accession #: P28798

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: N/A

Results: N/A

Binding Capacity: Immobilized Human BAFF, His Tag at 5 g/mL (100 L/well) can bind Cynomolgus / Rhesus macaque BCMA, Fc Tag with a linear range of 0.05-2 ng/ml

Unit Definition: N/A

Molecular Weight: ~65.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in distilled water

Amino acid sequence: Signal peptide and mouse progranulin (aa 1-589) is untagged. Reflects the native sequence with no additional amino acids.