Human CellExp™ CD111 / Nectin-1 / PVRL1, human recombinant | 7379

Poliovirus receptor-related protein 1 (PVRL1) is also known as Herpes virus entry mediator C (HveC), Herpesvirus Ig-like receptor (HIgR), Nectin-1, CD antigen CD111, PVRL1 / Nectin-1 / CD111 belongs to the nectin family. PVRL1 / Nectin-1 is a membrane protein with three extracellular immunoglobulin domains, a single transmembrane helix and a cytoplasmic tail. The protein can mediate Ca2+-independent cellular adhesion further characterizing it as IgSF cell adhesion molecule (IgSF CAM). PVRL1 is adhesion molecule found in a wide range of tissues. PVRL1 / Nectin-1 promote cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4.

7379 | Human CellExp CD111 / Nectin-1 / PVRL1 human recombinant DataSheet

Biomolecule/Target: CD111/Nectin-1/PVRL1

Synonyms: PVRL1, Nectin-1, CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12

Alternates names: PIGF, PGF, PLGF 1, Placenta Growth Factor-1

Taglines: Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers

NCBI Gene ID #: 5228

NCBI Gene Symbol: PGF

Gene Source: Human

Accession #: AAD30179

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.

Results: 0.5-10 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 29.7 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 g/l. The solution can then be diluted into other aqueous buffer

Amino acid sequence: N/A