Human CellExp™ CD319 / SLAMF7 / CRACC, Human Recombinant | 7376

SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.

7376 | Human CellExp CD319 / SLAMF7 / CRACC human recombinant DataSheet

Biomolecule/Target: CD319/SLAMF7/CRACC

Synonyms: SLAMF7, CD319, CS1, CRACC, 19A, FOAP-12

Alternates names: Apolipoprotein E2, apolipoprotein, apolipoproteins

Taglines: Mediates NK cell activation

NCBI Gene ID #: 348

NCBI Gene Symbol: ApoE

Gene Source: Human

Accession #: NM_000041

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Test in process

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 34.3 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.2 m filtered solution of 20 mM PB, 150 mM NaCl, 5% Trehalose, pH 7.4.

Reconstitution Instructions: Reconstitute in dHO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A