Human CellExp™ CEACAM1/CD66a, Extracellular Domain (ED), Human Recombinant | P1245

CEACAM1, also known as biliary glycoprotein I (BGP I) or CD66a, is an extensively studied cell surface molecule with established functions in multiple cancer types, as well as in various compartments of the immune system. The highly glycosylated CEACAM1 contains a 35-428 amino acid extracellular domain (ECD) which includes one N-terminal V-type Ig-like domain, followed by three C2-type Ig-like domains. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic binding, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

P1245 | Human CellExp CEACAM1/CD66a Extracellular Domain ED Human Recombinant DataSheet

Biomolecule/Target: CEACAM1

Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 1, BGP, BGP1, BGPI, CD66a, CEACAM1, CEACAM1, CEAM1

Alternates names: Collagen alpha-1(XVIII) chain

Taglines: Cell adhesion protein that plays role in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Human

Accession #:

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: ’s human Endostatin is biologically active when compared to standards. The activity as calculated by ECE migration inhibition was found to be 50,000 IU/mg.

Results: N/A

Binding Capacity: Immobilized Human TIM3 at 5 g/ml (100 l/well) can bind to biotinylated CEACAM1 (ED) with a linear range of 0.08-10 µg/ml.

Unit Definition: N/A

Molecular Weight: 20.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS pH 7.4

Reconstitution Instructions: N/A

Amino acid sequence: N/A