Human CellExp™CNTFR/CNTFR-alpha, human recombinant | 7836

Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.

7836 | Human CellExpCNTFR/CNTFR-alpha human recombinant DataSheet

Biomolecule/Target: CNTFR/CNTFR-alpha

Synonyms: CNTFR, CNTF R alpha

Alternates names: Peroxiredoxin 5, ACR1, AOEB116, B116, PLP, PMP20, PRDX6, PRXV, SBBI10.

Taglines: This receptor and its cognate ligand support the survival of neurons.

NCBI Gene ID #: 25824

NCBI Gene Symbol: PRDX5

Gene Source: Human

Accession #: P30044

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per g of the rh CNTFR alpha by the LAL method.

Activity (Specifications/test method): N/A

Biological activity: Specific activity: approximately 117-136 pmole/min/µg.

Results:

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Reconstitution Instructions: N/A

Amino acid sequence: MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL.