Human CellExp™ GFRA2 / GDNFRB, Human Recombinant | P1736

The GFRA2 receptor is a surface receptor attached to the cell membrane by a glycosylphosphatidylinositol linkage. GFRA2 is a receptor for glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) and mediates activation of the RET receptor tyrosine kinase. GFRA2 is a candidate target for the study of RET-associated diseases.

P1736 | Human CellExp™ GFRA2 / GDNFRB, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2

Alternates names: GDNF Family Receptor Alpha-2; GDNF Receptor Beta; Neurturin Receptor Alpha; RET Ligand 2

Taglines: Mediates activation of RET signaling

NCBI Gene ID #: 2675

NCBI Gene Symbol:

Gene Source: Human

Accession #: O00451

Recombinant: True

Source: HEK293 cells

Purity by SDS-PAGE: > 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1.0 EU per ug as determined by the LAL method

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: ~60 to 85 kDa due to glycosylation

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute using sterile deionized water. Do not vortex.

Amino acid sequence: Ser 22 to Ser 441 with C-terminal 6xHis Tag

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans