Human CellExp™ GITR / TNFRSF18, Human recombinant | 9231

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

9231 | Human CellExp GITR / TNFRSF18 Human recombinant DataSheet

Biomolecule/Target: GITR

Synonyms: AITR, GITR, TNFRSF18, CD357

Alternates names: C-reactive protein, CRP, PTX1, MGC88244, MGC149895, Cysteine-rich protein 2, Protein ESP1

Taglines: Tumor necrosis factor receptor superfamily member 18

NCBI Gene ID #: 1401

NCBI Gene Symbol: CRP

Gene Source: Human

Accession #: P02741

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 92%

Assay #2: N/A

Endotoxin Level: < 1 EU/g

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: N/A

Results: N/A

Binding Capacity: Immobilized Human GITR/TNFRSF18, His Tag at 2 µg/mL (100 µL/well) can bind r-Human GITR Ligand /TNFSF18 with a linear range of 0.8-25 ng/mL.

Unit Definition: N/A

Molecular Weight: 115.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

Reconstitution Instructions: N/A

Amino acid sequence: N/A