Human CellExp™ HDAC5, Catalytic Domain, Human Recombinant, Active | P1268

Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5- mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.

P1268 | Human CellExp HDAC5 Catalytic Domain Human Recombinant Active DataSheet

Biomolecule/Target: HDAC5

Synonyms: HDAC5, HD5, Histone Deacetylase 5

Alternates names: HDAC5, HD5, Histone Deacetylase 5, Antigen NY-CO-9, KIAA0600

Taglines: Key epigenetic regulator

NCBI Gene ID #: 3552

NCBI Gene Symbol: IL1A

Gene Source: Human

Accession #: P01583

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SEC

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): Deacetylation activity was determined using the Boc-K(TFA)-AMC substrate.

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 45 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In 30 mM HEPES, 140 mM NaCl, 10 mM KCl, 3% glycerol, 0.25 mM TCEP, pH 7.6

Reconstitution Instructions: N/A

Amino acid sequence: N/A