Human CellExp™ IL-7 R alpha / CD127, IgG2a Fc Tag, Human Recombinant | P1238

Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

P1238 | Human CellExp IL-7 R alpha / CD127 IgG2a Fc Tag Human Recombinant DataSheet

Biomolecule/Target: IL7R

Synonyms: IL7Ra, CD127

Alternates names: Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt, PBEF

Taglines: Receptor for interleukin-7

NCBI Gene ID #: 59027

NCBI Gene Symbol: NAMPT

Gene Source: Mouse

Accession #: Q99KQ4

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Mimics insulin effects in differentiating 3T3-L1 cells.

Results: N/A

Binding Capacity: Immobilized Human IL-7, Tag Free at 2 g/mL (100 L/well) can bind Human IL-7 R alpha, mouse IgG2a Fc tag with a linear range of 4-31 ng/mL

Unit Definition: N/A

Molecular Weight: 55.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in PBS to the concentration of 0.1-1 mg/ml.

Amino acid sequence: N/A