Human CellExp™ KRAS, Human Recombinant | P1198

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. It plays an important role in the regulation of cell proliferation and promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes in colorectal cancer cells.

P1198 | Human CellExp KRAS Human Recombinant DataSheet

Biomolecule/Target: KRAS

Synonyms: NS, NS3, CFC2, RALD, KRAS1, KRAS2, RASK2, KI-RAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, c-Ki-ras2

Alternates names: VGR, VGR1, BMP-6, VG-1-related protein

Taglines: A Ras family protein involved in regulation of cell proliferation.

NCBI Gene ID #: 654

NCBI Gene Symbol: BMP6

Gene Source: Human

Accession #: P22004

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: ’s recombinant human BMP-6 is biologically active. The ED as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.

Results: 2-12 µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: monomer (15 kDa), dimer (30 kDa)

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS pH 7.4

Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A