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Human CellExp™ MMP-9, human recombinant | 7246

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SKU:
26-7246-GEN
Availability:
Usually shipped in 5 working days
zł3,750.00 - zł35,694.00

Description

Matrix metallopeptidase 9 (MMP-9) is secreted from neutrophils, macrophages and a number of transformed cells. It is the most complex MMP family member in terms of domain structure and regulation of its activity. MMP family is involved in the breakdown of extracellular matrix in normal physiological processes as well as in disease processes. Most MMPs are secreted as inactive pro-proteins which are activated by the cleavage of extracellular proteinases. MMP-9 degrades various substrates including Gelatin, collagen types IV and V, and elastin. It is involved in inflammatory responses, tissue remodeling, wound healing, tumor growth and diseases including systemic lupus erythematosus, rheumatoid arthritis, and multiple sclerosis. MMP-9 is regarded as a potential therapeutic target and a biomarker of disease status.

7246 | Human CellExp MMP-9 human recombinant DataSheet

Biomolecule/Target: MMP-9

Synonyms: MMP9, CLG4B, GelB, MANDP2, MMP-9, Matrix Metalloproteinase-9

Alternates names: Small ubiquitin-related modifier 1, SUMO-1, Sentrin, Ubiquitin-like protein SMT3C, SMT3 homolog 3, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein UBL1, GAP-modifying protein 1, GMP1, SUMO1, SMT3C, SMT3H3, UBL1, PIC1, SMT3, DAP-1, OFC10, SENP2.

Taglines: Involved in the breakdown of extracellular matrix

NCBI Gene ID #: 7341

NCBI Gene Symbol: SUMO1

Gene Source: Human

Accession #: P63165

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): N/A

Biological activity: Typical in vitro concentrations for conjgate formation is 10-50 µM depending on conditions.

Results: 10-50 µM

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 11.1 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized from 0.22 m filtered PBS (pH 7.4) with 5% trehalose.

Reconstitution Instructions: N/A

Amino acid sequence: N/A

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Additional Information

Storage:
-20°C
Shipping:
Gel Pack
Shelf Life:
12 months
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