Human CellExp™ MSR1/CD204, human recombinant | 7390

Macrophage scavenger receptor 1 (MSR1) also known as CD204, SCARA1, SR-A, and is class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. Defects in MSR1 may be a cause of prostate cancer (PC) or Barrett esophagus (BE).

7390 | Human CellExp MSR1/CD204 human recombinant DataSheet

Biomolecule/Target: MSR1/CD204

Synonyms: MSR1, CD204, SCARA1, SR-A, phSR1, phSR2

Alternates names: Small ubiquitin-related modifier 1, SUMO-1, Sentrin, Ubiquitin-like protein SMT3C, SMT3 homolog 3, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein UBL1, GAP-modifying protein 1, GMP1, SUMO1, SMT3C, SMT3H3, UBL1, PIC1, SMT3, DAP-1, OFC10, SENP2.

Taglines: Mediates the endocytosis of modified low density lipoproteins (LDLs)

NCBI Gene ID #: 7341

NCBI Gene Symbol: SUMO1

Gene Source: Human

Accession #: P63165

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Typical in vitro concentrations for conjgate formation is 10-50 µM depending on conditions.

Results: 10-50 µM

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 11.1 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: N/A

Amino acid sequence: N/A