Human CellExp™ Nectin-4, Human Recombinant | P1389

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

P1389 | Human CellExp Nectin-4 Human Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: NECTIN4, LNIR, PRR4, PVRL4

Alternates names: SUMO3; SMT3A; SMT3H1; SUMO-3, SMT3 homolog 1, SUMO-2, Ubiquitin-like protein SMT3B

Taglines: Transmembrane glycoprotein that involved in cell adhesion through trans-homophilic and -heterophilic interactions

NCBI Gene ID #:

NCBI Gene Symbol: SUMO3

Gene Source: Human

Accession #:

Recombinant: FALSE

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: Less than 1.0 EU per g by the LAL method.

Activity (Specifications/test method): N/A

Biological activity: Typical in vitro concentrations for conjgate formation is 10-50 µM depending on conditions.

Results: 10-50 µM

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 11.6 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized

Reconstitution Instructions: N/A

Amino acid sequence: N/A