Human CellExp™ PD-L1 /CD274 /B7-H1, human recombinant | 7429

Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1). It has been identified as the ligand for PD1/PDCD1 (Cat. No. 7498) and has been demonstrated to play a role in the regulation of immune r

7429 | Human CellExp PD-L1 /CD274 /B7-H1 human recombinant DataSheet

Biomolecule/Target: PD-L1 /CD274 /B7-H1

Synonyms: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1

Alternates names: EPG, Epigen, PRO9904, ALGV3072, FLJ75542, EPGN, Epithelial mitogen.

Taglines: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

NCBI Gene ID #: 255324

NCBI Gene Symbol: EPGN

Gene Source: Human

Accession #: Q6UW88

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 0.9

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED for this effect is 150-300 ng/ml.

Results: 150-300 ng/ml

Binding Capacity: Immobilized Human PD-L1, His Tag at 5 g/mL (100 L/well) can bind Human PD-1, His Tag with a linear range of 0.15-1.25 g/mL.

Unit Definition: N/A

Molecular Weight: 7.9 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS pH 7.4

Reconstitution Instructions: Reconstitute in sterile dHO not less than 100 g/ml.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Amino acid sequence: N/A