Human CellExp™ Tim-1, Fc Tag, Human Recombinant | P1352

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. TIM-1 (T cell-immunoglobulinmucin; also KIM-1 and HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of TIM1. One is a long (359 aa) kidney form termed TIM-1b, and one is a short (334 aa) liver form termed TIM-1a. TIM-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.

P1352 | Human CellExp Tim-1 Fc Tag Human Recombinant DataSheet

Biomolecule/Target: Tim-1

Synonyms: TIM1; KIM1; TIMD1; Hepatitis A Virus Cellular Receptor 1; HAVcr-1; T Cell Immunoglobulin and Mucin Domain-containing Protein 1; T Cell Membrane Protein 1

Alternates names: CFP, Cyan Fluorescent Protein

Taglines: May be involved in the moderation of asthma and allergic diseases

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source:

Accession #:

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <5 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 31.3 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.2 m-filtered solution in PBS

Reconstitution Instructions: Reconstitute with dHO to 1 mg/ml

Amino acid sequence: N/A