Human CellExp™ TROP-2 / TACSTD2, Human recombinant | P1132

Tumor-associated calcium signal transducer 2 (TACSTD2) is also known as Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1 (M1S1), Pancreatic carcinoma marker protein GA733-1, which belongs to the EPCAM family. TACSTD2 contains one thyroglobulin type-1 domain. TACSTD2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. TACSTD2 transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of TACSTD2 result in Gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness

P1132 | Human CellExp TROP-2 / TACSTD2 Human recombinant DataSheet

Biomolecule/Target: TACSTD2

Synonyms: TACSTD2, GA733-1, M1S1, TROP2

Alternates names: Protein phosphatase 1A (formerly 2C), human recombinant PP2C alpha, hrPP2C alpha, human PP2C alpha, recombinant PP2C alpha, magnesium-dependent, alpha isoform, PPM1A, PP2CA, PP2C-ALPHA.

Taglines: A cell surface glycoprotein function as a growth factor receptor.

NCBI Gene ID #: 5494

NCBI Gene Symbol: PPM1A

Gene Source: Human

Accession #: P35813

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): N/A

Biological activity: >8,000 units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 46.6 kDa (418aa)

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4.

Reconstitution Instructions: N/A

Amino acid sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWIL FFAVYDGHAG SQVAKYCCEH LLDHITNNQD FKGSAGAPSV ENVKNGIRTG FLEIDEHMRV MSEKKHGADR SGSTAVGVLI SPQHTYFINC MGAF LDKPKMEKHN AQGQGNGLRY GLSSMQGWRV EMEDAHTAVI GLPSGLESWS GDSRGLLCRN RKVHFFTQDH KPSNPLEKER IQNAGGSVMI QRVNGSLAVS RALGDFDYKC VHGKGPTEQL VSPEPEVHDI ERSEEDDQFI ILACDGIWDV MGNEELCDFV RSRLEVTDDL EKVCNEVVDT CLYKGSRDNM SVILICFPNA PKVSPEAVKK EAELDKYLEC RVEEIIKKQG EGVPDLVHVM RTLASENIPS LPPGGelASK RNVIEAVYNR LNPYKNDDTD STSTDDMW