Human Hec1 | P1671

Hec1 is a component of the kinetochore outer layer, which is required for chromosome segregation and spindle checkpoint activity. It is required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. It is overexpressed in a variety of human cancers and maybe used for the prognosis of primary breast cancer.

P1671 | Human Hec1 DataSheet

Biomolecule/Target :

Synonyms: Kinetochore protein NDC80 homolog; Highly expressed in cancer protein; Kinetochore protein Hec1; HsHec1; Kinetochore-associated protein 2; Retinoblastoma-associated protein HEC

Alternates names: Kinetochore protein NDC80 homolog; Highly expressed in cancer protein; Kinetochore protein Hec1; HsHec1; Kinetochore-associated protein 2; Retinoblastoma-associated protein HEC

Taglines: A component of the kinetochore outer layer

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Human

Accession #: O14777

Recombinant: 1

Source: E.coli

Purity by SDS-PAGE: ≥ 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

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Binding Capacity:

Unit Definition:

Molecular Weight: 41.01 kDa

Concentration:

Appearance: Lyophilized protein

Physical form description:

Reconstitution Instructions: Reconstitute in sterile water to a concentration of 1 mg/ml.

Amino acid sequence: The target protein is expressed with the sequence Pro290-Glu642 of human Hec1 with a His tag at the N-terminus.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans