Human IL-33 protein | PRP1018

Human IL-33 protein | PRP1018 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from human IL-33 isoform (O95760) (Ser112-Thr270) was expressed.

Activity: N/A

protein Lenght: The recombinant human IL-33 consists of 160 amino acids (N-Met) and has a predicted molecular mass of 18.1 kDa. The apparent molecular mass of the human IL-33 is approximately 18 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Preparation: E. coli

Purity: >98 % as determined by SDS-PAGE

Formulation: Lyophilized from sterile 20 mM Tris, 50 mM NaCl, pH 5.0, 1 mM DTT, 1 mM EDTA.

Kit Component: N/A

Features & Benefits : Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.

Molecular Weight: 18 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL33 protein protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human IL-33 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.8% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial enules), is a proinflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researchers suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also plays a pivotal role in helminthic infection and allergic disorders.

Alternative Names: C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV; Interleukin-33; IL33

Search Names: C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV; Interleukin-33; IL33

Tag: IL-33