Human Recombinant PIN4 | 6387

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, Pin4 protein binds to double-stranded DNA under physiological salt conditions.

6387 | Human Recombinant PIN4 DataSheet

Biomolecule/Target: N/A

Synonyms: Human Recombinant PIN4

Alternates names: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 isoform 2, Parvulin-14, Parvulin-17, PPIase Pin4, hEPVH, PAR14, PAR17

Taglines: Vital for cell cycle regulation

NCBI Gene ID #: 16171

NCBI Gene Symbol: IL17

Gene Source: Human

Accession #: Q62386

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Specific activity is > 300 nmoles/min/mg

Results: >300 nmoles/min/mg

Binding Capacity: N/A

Unit Definition: One unit is defined as the amount of enzyme that cleaves 1 µmole of Suc-AAFP-pNA per minute at 25°C in Tris HCl pH 8.0 using chymotrypsin.

Molecular Weight: 18.8 kDa (176 aa, 1-156 aa + NT His Tag)

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 mM PMSF, 1 mM DTT and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MPMAGLLKGL VRQLERFSVQ QQASKMPPKG KSGSGKAGKG GAASGSDSAD KKAQGPKGGG NAVKVRHILC EKHGKIMEAM EKLKSGMRFN EVAAQYSEDK ARQGGDLGWM TRGSMVGPFQ EAAFALPVSG MDKPVFTDPP VKTKFGYHII MVEGRK