Human Recombinant PPP1CA | 6370

Serine/Threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) is crucial for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The PPP1CA protein may have a significant role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.

6370 | Human Recombinant PPP1CA DataSheet

Biomolecule/Target: N/A

Synonyms: Human Recombinant PPP1CA

Alternates names: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PP1alpha, PPP1A.

Taglines: Crucial for cell division

NCBI Gene ID #: 25465

NCBI Gene Symbol: IL17A

Gene Source: Human

Accession #: Q61453

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Specific activity: >3,000 units/mg.

Results: >3,000 units/mg

Binding Capacity: N/A

Unit Definition: One unit will hydrolyze 1 nmole of p-nitrophenylphosphatate (pNPP) per minute at 37°C, pH 7.5 using 10 mM of substrate.

Molecular Weight: 39.7 kDa (350 aa, 1-330 aa + NT His-Tag)

Concentration: 0.25 mg/ml

Appearance: Liquid

Physical form description: 0.25 mg/ml solution in 50 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 1 mM DTT, 0.15 M NaCl, 1 mM MnCl2 and 0.1 mM PMSF.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MSDSEKLNLD SIIGRLLEVQ GSRPGKNVQL TENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLFL GDYVDRGKQS LETICLLLAY KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRYNIKLWK TFTDCFNCLP IAAIVDEKIF CCHGGLSPDL QSMEQIRRIM RPTDVPDQGL LCDLLWSDPD KDVQGWGEND RGVSFTFGAE VVAKFLHKHD LDLICRAHQV VEDGYEFFAK RQLVTLFSAP NYCGEFDNAG AMMSVDETLM CSFQILKPAD KNKGKYGQFS GLNPGGRPIT PPRNSAKAKK