Description
Peroxiredoxin-1 in humans is encoded by the PRDX1 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. It protein may also have a proliferative effect and play a role in cancer development or progression.
6323 | Human Recombinant PRDX 1 DataSheet
Biomolecule/Target: N/A
Synonyms: Human Recombinant PRDX 1
Alternates names: Peroxiredoxin 1, MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Thioredoxin peroxidase 2.
Taglines: An antioxidant protein implicated in a variety of cellular responses
NCBI Gene ID #: 301289
NCBI Gene Symbol: IL17 or CTLA-8
Gene Source: Human
Accession #: Q61454
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Specific activity: approximately 600-670 pmole/min/µg.
Results: N/A
Binding Capacity: N/A
Unit Definition: Specific activity is defined as the amount of hydroperoxide that 1 µg of enzyme can reduce at 25°C for 1 minute.
Molecular Weight: 24 kDa
Concentration: 1 mg/ml
Appearance: Liquid
Physical form description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 20% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK