Human Recombinant PRDX 3 | 6320

Peroxiredoxin-3 (Prdx3) is a mitochondrial member of the antioxidant family of thioredoxin peroxidases that uses mitochondrial thioredoxin-2 (Trx2) as a source of reducing equivalents to scavenge hydrogen peroxide (H2O2). It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

6320 | Human Recombinant PRDX 3 DataSheet

Biomolecule/Target: N/A

Synonyms: Human Recombinant PRDX 3

Alternates names: Thioredoxin-dependent peroxide Reductase, mitochondrial, PRDX3, PRX III, Antioxidant protein 1 (AOP-1).

Taglines: An antioxidant protein implicated in a variety of cellular responses

NCBI Gene ID #: 501996

NCBI Gene Symbol: IL17E

Gene Source: Human

Accession #: XP_577423

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Specific activity: approximately 82-83 pmole/min/µg.

Results: N/A

Binding Capacity: N/A

Unit Definition: Specific activity is defined as the amount of hydroperoxide that 1 µg of enzyme can reduce at 25°C for 1 minute.

Molecular Weight: 21.5 kDa

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ.