Human recombinant UBE2E2 (UbcH8) | 6438

Ubiquitin-conjugating enzyme E2 (UBE2E2) is a protein that in humans is encoded by the UBE2E2 gene. Amino acid sequence within the UBC domain of UBE2E2 shares over 90% identity with human UbcH6, mouse UbcM2, and Drosophila UbcD2, whereas the N-terminal region shows little amino acid sequence similarity with known proteins. The UBE2E2 protein forms a thioester bond with ubiquitin in an E1-dependent manner and mediates the transfer of ubiquitin from a ubiquitin-activating enzyme (E1) to a substrate protein or E3 ligase.

6438 | Human recombinant UBE2E2 UbcH8 DataSheet

Biomolecule/Target: N/A

Synonyms: Human recombinant UBE2E2 (UbcH8)

Alternates names: RIG-B, UBCH8, MGC40331, UBE2L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrier protein L6, and Retinoic acid-induced gene B protein.

Taglines: Ubiquitin conjugating enzyme involved in conjugation of ubiquitin to target substrates.

NCBI Gene ID #: 60505

NCBI Gene Symbol: IL21

Gene Source: Human

Accession #: Q9ES17

Recombinant: Yes

Source: N/A

Purity by SDS-PAGEs: 95%

Assay: RP-HPLC

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Protein concentration of 100 nM - 1 µM is recommended for in vitro conjugation.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 22.255 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: 75 µL of a 40 µM solution (3 nmoles) in 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT and 10% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: N/A