Human SMAC/Diablo | P1602

Smac/Diablo is a proapoptotic protein. It promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway. It acts by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity.

P1602 | Human SMAC/Diablo DataSheet

Biomolecule/Target :

Synonyms: ITGA6:ITGB4; alpha-6/beta-4,Diablo isoform 1, Diablo homolog, DIABLO S, Mitochondrial Smac protein, Smac, Direct IAP binding protein with low pI, Second mitochondria-derived activator of caspase

Alternates names: ITGA6:ITGB4; alpha-6/beta-4,Diablo isoform 1, Diablo homolog, DIABLO S, Mitochondrial Smac protein, Smac, Direct IAP binding protein with low pI, Second mitochondria-derived activator of caspase

Taglines: A proapoptotic protein

NCBI Gene ID #: NP_063940

NCBI Gene Symbol:

Gene Source: Human

Accession #: Q9NR28

Recombinant: YES

Source: E.coli

Purity by SDS-PAGE: >95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 22 kDa (199 aa)

Concentration: 1 mg/ml

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: 56-239 aa

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans