Human Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) ELISA Kit | AE13994HU

Human Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) ELISA Kit | AE13994HU | Gentaur UK, US & Europe Distribution

Species Reactivity: Human (Homo sapiens)

Abbreviation: TNFRSF6B

Alternative Name: hCG_2044836; DCR3; DJ583P15.1.1; M68; TR6; OTTHUMP00000031583|decoy receptor 3|tumor necrosis factor receptor superfamily; member 6b

Application: ELISA

Range: Request Information

Sensitivity: Request Information

Intra-Assay: ≤5.6%

Inter-Assay: ≤7.7%

Recovery: 0, 81

Sample Type: Serum, Plasma, Other biological fluids

Detection Method: Sandwich

Analysis Method : Quantitive

Test Principale: This assay employs a two-site sandwich ELISA to quantitate TNFRSF6B in samples. An antibody specific for TNFRSF6B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTNFRSF6B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFRSF6B is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFRSF6B bound in the initial step. The color development is stopped and the intensity of the color is measured.

Product Overview: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5 UTR, have been observed for this gene.

Stability: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. The loss rate was determined by accelerated thermal degradation test. Keep the kit at 37°C for 4 and 7 days, and compare O.D.values of the kit kept at 37°C with that of at recommended temperature. (referring from China Biological Products Standard, which was calculated by the Arrhenius equation. For ELISA kit, 4 days storage at 37°C can be considered as 6 months at 2 - 8°C, which means 7 days at 37°C equaling 12 months at 2 - 8°C) .