Hydroxy Dynasore | B2642

Hydroxy Dynasore is an analog of Dynasore (Cat. No. 1900) that acts as a potent dynamin inhibitor (IC₅₀ values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons.

Hydroxy Dynasore is an analog of Dynasore (Cat. No. 1900) that acts as a potent dynamin inhibitor (IC₅₀ values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons.

B2642 | Hydroxy Dynasore DataSheet

Alternate Name/Synonyms: Dyngo 4a, 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide

Appearance: Yellow solid

Formulation:

CAS Number: 1256493-34-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₄N₂O₅

Molecular Weight: 338.31

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >30 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A dynamin inhibitor

MDL Number:

PubChem CID: 136227923

SMILES: C1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3O)O)O)O

InChi: InChI=1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+

InChi Key: UAXHPUSKEWEOAP-DJKKODMXSA-N