Hydroxychloroquine sulfate | B2051

Hydroxychloroquine is a synthetic quinine derivative commonly used as an antimalarial drug. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. It inhibits autophagy and induces autophagic cell death (IC₅₀ = 30 µM), suggesting potential applications in research and medicine.

Hydroxychloroquine is a synthetic quinine derivative commonly used as an antimalarial drug. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. It inhibits autophagy and induces autophagic cell death (IC₅₀ = 30 µM), suggesting potential applications in research and medicine.

B2051 | Hydroxychloroquine sulfate DataSheet

Alternate Name/Synonyms: 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate; HCQ

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 747-36-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₆ClN₃O • H₂SO₄

Molecular Weight: 434

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H2O (>20 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An autophagy inhibitor

MDL Number: MFCD00078203

PubChem CID: 12947

SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

InChi: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChi Key: JCBIVZZPXRZKTI-UHFFFAOYSA-N