I-TAC, human recombinant | 4203

Human Interferon-inducible T cells chemoattractant (I-TAC) is a novel non-ELR CXC chemokine. ’s human I-TAC is a 8.3 kDa protein, containing 73 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

4203 | I-TAC human recombinant DataSheet

Biomolecule/Target: I-TAC

Synonyms: Human I-TAC, I-TAC, ITAC, I TAC, I-TAC, I-TAC, recombinant human I-TAC, recombinant I-TAC

Alternates names: Macrophage Colony Stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF.

Taglines: A cytokine chemotactic for activated T cells

NCBI Gene ID #: 1435

NCBI Gene Symbol: CSF1

Gene Source: Human

Accession #: P09603

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: 95%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g

Activity (Specifications/test method): N/A

Biological activity: The EC50 is typically 0.5 to 4 ng/mL for this protein with specific activity determined by the dose dependent stimulation of the proliferation of murine M-NFS-60 cells (Mouse Myeloid Leukemia indicator cell line)

Results: 0.5 to 4 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: This protein has 223 amino acids (Glu 33 - Arg 255) with a 6x-His tag at C-terminus, and a calculated MW of 26 kDa. The protein migrates to 35-45 kDa under reducing and non-reducing conditions (SDS-PAGE) due to glycosylation

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.

Amino acid sequence: N/A