ICAM-1 polyclonal Antibody | BS90682

ICAM-1 polyclonal Antibody | BS90682 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC FC

Application Range: WB:1:500-1:1,000 ICC:1:200 IHC:1:200 FC:1:50-1:100

Background: ICAM-1 is a member of the immunoglobulin superfamily, the superfamily of proteins including antibodies and T-cell receptors. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor (TNF) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. More recently, ICAM-1 has been characterized as a site for the cellular entry of human rhinovirus. ICAM-1 and soluble ICAM-1 have antagonistic effects on the tight junctions forming the blood-testis barrier, thus playing a major role in spermatogenesis. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH) .

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: ICAM-1 polyclonal Antibody detects endogenous levels of ICAM-1 protein.

Molecular Weight: 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ICAM-1, Antigen identified by monoclonal, BB2, BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Intercellular adhesion molecule 1, Major group rhinovirus receptor, MALA 2, MALA2, MyD 10, MyD10, P3.58, Surface antigen of activated B cells, BB2,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: