Description
ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Recombinant human ICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
7349 | ICAM2 human recombinant DataSheet
Biomolecule/Target: ICAM2
Synonyms: Intercellular adhesion molecule 2, CD102
Alternates names: Intercellular adhesion molecule 2, CD102
Taglines: Plays a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion
NCBI Gene ID #: 90865
NCBI Gene Symbol: IL33
Gene Source: Human
Accession #: O95760
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Test in process
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 24.8 kDa (225 aa, 22-223 aa + His Tag), confirmed by MALDI-TOF.
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 1 mM DTT and 10% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSSDEKVFE VHVRPKKLAV EPKGSLEVNC STTCNQPEVG GLETSLDKIL LDEQAQWKHY LVSNISHDTV LQCHFTCSGK QESMNSNVSV YQPPRQVILT LQPTLVAVGK SFTIECRVPT VEPLDSLTLF LFRGNETLHY ETFGKAAPAP QEATATFNST ADREDGHRNF SCLAVLDLMS RGGNIFHKHS APKMLEIYEP VSDSQ