Icariin | B2261

Icariin is the active component of the Chinese medicinal plant E. brevicornum that acts as an inhibitor of human phosphodiesterase 5 (PDE5) (IC₅₀ = 5.9 μM). Icariin also promotes the growth and proliferation of neural stem cells from rat hippocampus in a dose-dependent manner.

Icariin is the active component of the Chinese medicinal plant E. brevicornum that acts as an inhibitor of human phosphodiesterase 5 (PDE5) (IC₅₀ = 5.9 μM). Icariin also promotes the growth and proliferation of neural stem cells from rat hippocampus in a dose-dependent manner.

B2261 | Icariin DataSheet

Alternate Name/Synonyms: 4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

Appearance: Light yellow to yellow solid

Formulation: N/A

CAS Number: 489-32-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₃H₄₀O₁₅

Molecular Weight: 676.66

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (>50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A human phosphodiesterase 5 (PDE5) inhibitor

MDL Number: MFCD00210516

PubChem CID: 5318997

SMILES: CC1C(C(C(C(O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)OC4C(C(C(C(O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O

InChi: InChI=1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1

InChi Key: TZJALUIVHRYQQB-XLRXWWTNSA-N