ID-8 | 2562

ID-8 is a cell culture supplement that can sustain self-renewal and pluripotency of mouse embryonic stem cells in vitro. At 10 μM it stimulates proliferation in serum-free media at a steady rate for more than 30 days. Also inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).

ID-8 is a cell culture supplement that can sustain self-renewal and pluripotency of mouse embryonic stem cells in vitro. At 10 μM it stimulates proliferation in serum-free media at a steady rate for more than 30 days. Also inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).

2562 | ID-8 DataSheet

Alternate Name/Synonyms: 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

Appearance: Yellow solid

Formulation: N/A

CAS Number: 147591-46-6

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄N₂O₄

Molecular Weight: 298.29

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A stem cell modulator

MDL Number: MFCD00593367

PubChem CID: 791637

SMILES: CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]

InChi: InChI=1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3

InChi Key: VVZNWYXIOADGSW-UHFFFAOYSA-N