IDAS Antibody (N-term) [AMM08633G]

IDAS Antibody (N-term) [AMM08633G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, Rat

Specificity: This IDAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-46 amino acids from the N-terminal region of human IDAS.

Cellular Localisation: Nucleus. Note=Excluded from the nucleolus

Molecular Weight: 41720

Clone: Polyclonal

Gene Name: MCIDAS (HGNC:40050)

Gene ID: 345643

Function: Transcription regulator specifically required for multiciliate cell differentiation (PubMed:25048963) . Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome- mediated acentriolar pathway (PubMed:25048963) . Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN