IFN beta polyclonal Antibody | BS62219

IFN beta polyclonal Antibody | BS62219 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000

Background: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IFN beta  polyclonal Antibody detects endogenous levels of IFN beta protein.

Molecular Weight: ~ 22 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Interferon beta; Interferon β; IFN-beta; IFN-β; IFNβ; Fibroblast interferon; IFB; IFNB

Immunogen: Synthetic peptide, corresponding to Human IFN beta.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: