Description
IFNLR1 Antibody | 13-419 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-228 of human IFNLR1 (NP_734464.1) .
Research Area: Chemokines & Cytokines, Immunology, Innate Immunity
Tested Application: WB
Application: WB: 1:1000 - 1:4000
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: Jurkat
Positive Control 3: MCF7
Positive Control 4: Mouse lung
Positive Control 5: Mouse heart
Positive Control 6: Mouse small intestine
Molecular Weight: Observed: 53kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: IL28RA, CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL28RA, IL-28R1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A) , interleukin 28B (IL28B) , and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.