IFNLR1 Antibody | 13-419

IFNLR1 Antibody | 13-419 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-228 of human IFNLR1 (NP_734464.1) .

Research Area: Chemokines & Cytokines, Immunology, Innate Immunity

Tested Application: WB

Application: WB: 1:1000 - 1:4000

Specificiy: N/A

Positive Control 1: HT-29

Positive Control 2: Jurkat

Positive Control 3: MCF7

Positive Control 4: Mouse lung

Positive Control 5: Mouse heart

Positive Control 6: Mouse small intestine

Molecular Weight: Observed: 53kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: IL28RA, CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL28RA, IL-28R1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A) , interleukin 28B (IL28B) , and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.