IFT88 Antibody (C-term) [APR30734G]

IFT88 Antibody (C-term) [APR30734G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This IFT88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 791-820 amino acids from the C-terminal region of human IFT88.

Cellular Localisation: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q61371}. Note=Colocalizes with ENTR1 and gamma- tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome.

Molecular Weight: 93192

Clone: Polyclonal

Gene Name: IFT88

Gene ID: 8100

Function: Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

Summary: Tissue Location: Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, IF

Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50

Synonyms: Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, IFT88, TG737, TTC10