IKBβ polyclonal Antibody | BS90694

IKBβ polyclonal Antibody | BS90694 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC IP

Application Range: WB:1:1,000 ICC:1:50-1:200 IHC:1:50-1:200

Background: On the basis of both functional and structural considerations, members of the IkB family of proteins can be divided into four groups. The first of these groups, IkB-α, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kB sites, suggesting that the IkB-α family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkB family is represented by a protein designated IkB-β. The third group of IkB proteins is represented by IkB-ε, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IkB family member, IkB-é, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: IKBβ polyclonal Antibody detects endogenous levels of IKBβ protein.

Molecular Weight: 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NF-kappa-BIB, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, TRIP-9, NFKBIB, I kappa B beta, I-kappa-B-beta, IkappaBbeta, IKB beta, IkB-B, IkB-beta, IKBB, IKBB, IkBbeta, NF kappa BIB, NF-kappa-B inhibitor beta, NF-kappa-BIB, Nfkbib, Thyroid receptor interacting protein 9, Thyroid receptor-interacting protein 9, TR interacting protein 9, TR-interacting protein 9, TRIP-9, TRIP9,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: PI3K AKT signaling,Toll-like Receptor signaling,