Additional Information
Size: |
100 µl |
Target: |
IKK alpha + IKK beta (pSer176/177) |
Conjugate: |
Unconjugated |
Research Area: |
Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | Cell Signaling | Epigenetics and Nuclear Signaling | Nuclear Signaling Pathways | NFkB Pathway | IKK | Cardiovascular System | Atherosclerosis | Vascular Inflammation | Inflammat |
Alternative Name: |
IKKA Antibody, IKKB Antibody, CHUK Antibody, IKKα/β Antibody, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor Antibody, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit Antibody, I Kappa B Kinase 1 Antibody, TCF16 Antib |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human IKK alpha + IKK beta proteins around the phosphorylation sites of IKKα at serine 176 (pSer176) and IKKβ at serine 177 (pSer177). |
Immunogen Species: |
Human |
Applications: |
WB, IHC, ELISA |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of IKKα only when phosphorylated at serine 176 (pSer176) and IKKβ only when phosphorylated at serine 177 (pSer177). Detects a band at ~80 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Nucleus, Cytoplasm, Cytosol, Ikappab Kinase Complex, Nucleoplasm, Plasma Membrane, Cd40 Receptor Complex, Cytoplasmic Side Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane Raft |
Tissue Specificity: |
Alpha: Widely expressed. Beta: Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood. |
Accession Number: |
NP_001269.3/NP_001177649.1 |
Gene ID: |
1147/3551 |
Swiss-Prot: |
O15111/O14920 |
Field of Use: |
For in vitro research use only. |