IL-1 beta Antibody | 5129

IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues.

5129 | IL-1 beta Antibody DataSheet

Antibody Target: IL-1b

Target Alternative Name: IL-1 beta, IL1 beta, IL 1 beta, Interluekin-1 beta, Interluekin 1 beta, interluekin

Tag Line:

Category: Interluekin

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Mouse

Immunogen Sequence: E. coli expressed murine IL-1?

Accession #: CAA28637

Gene ID: 52667

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-murine IL-1? polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5%BSA and 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot, Neutralization

Positive Control:

Application And Usages: Western blot analysis (0.5-4 µg/ml). Recombinant murine IL-1? (Cat.# 4129-10) can be used as a positive control. Per researcher’s feedback, the antibody can also be used in neutralization studies. However, the optimal conditions should be determined individually.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified