BW
IL-12A (T65) polyclonal Antibody | BS3490
- SKU:
- BW-BS3490
- Availability:
- Usually ships in 5 working days
Description
IL-12A (T65) polyclonal Antibody | BS3490 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-γ (IFN-γ) . It also activates production of tumor necrosis factor α (TNFα) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-γ. IL-12 also has anti-angiogenic activity since the production of IFN-γ increases the production of inducible protein-10 (IP-10) . IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IL-12A (T65) polyclonal Antibody detects endogenous levels of IL-12A protein.
Molecular Weight: ~ 25 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell stimulatory factor chain 1; NKSF1; IL12A; NKSF1
Immunogen: Synthetic peptide, corresponding to amino acids 32-81of Human IL-12A.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: