IL-17 polyclonal Antibody | BS90701

IL-17 polyclonal Antibody | BS90701 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Application: WB IHC FC

Application Range: WB:1:500-1:2000 IHC:1:50-1:200 FC:1:50-1:100

Background: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: IL-17 polyclonal Antibody detects endogenous levels of IL-17 protein.

Molecular Weight: Predicted band size 17.5 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: IL-17, IL-17A, CTLA-8, IL17A, CTLA8, IL17, CTLA 8, CTLA-8, CTLA8, Cytotoxic T lymphocyte associated antigen 8, Cytotoxic T lymphocyte associated protein 8, Cytotoxic T lymphocyte associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL 17A, IL-17, IL-17A, IL17, IL17, Il17a, Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8), Interleukin 17A, Interleukin-17A, Interleukin17, Interleukin17A, OTTHUMP00000016597, OTTMUSP00000046003,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: