IL-17A Antibody| F42568-0.08ML/RQ4021

IL-17A Antibody| F42568-0.08ML/RQ4021 | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Bovine

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the IL-17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This IL-17 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 61-87 from the human protein was used as the immunogen for this IL-17 antibody.

Storage: Aliquot the IL-17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A