IL-18 Antibody | 5180R

IL-18 (IFN-gamma-inducing factor, IGIF) is a novel proinflammatory cytokine that a?gments natural killer (NK) activity in spleen cells. It also has other biological properties such as activation of NF-kB, stimulation of Fas ligand expression, induction of CC and CXC chemokines. IL-18 increases production of competent HIV. IL-18 is related to the IL-1 family. One of the IL-18 receptor chains is the IL-1 receptor-related protein, a member of the IL-1R family. Like IL-1?, IL-18 is first synthesized as a leaderless precursor requiring the IL-1? converting enzyme (ICE) for cleavage into an active molecule. IL-18 may play a role in tissue injury in inflammatory reactions.

5180R | IL-18 Antibody DataSheet

Antibody Target: IL-18

Target Alternative Name: IL-18, IL18, IL 18, Interluekin-18, Interluekin 18, interluekin

Tag Line:

Category: Interluekin

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Mouse

Immunogen Sequence: Synthetic peptide of mouse IL-18

Accession #: P70380

Gene ID: 16173

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: 100 µg affinity purified rabbit anti-mouse IL-18 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.05% sodium azide.

Purification: Affinity purified

Application: Western blot, Immunoprecipitation, Neutralization

Positive Control:

Application And Usages: Western blot analysis (0.5-4 µg/ml), immunoprecipitation (2-5 µg/ml), and neutralization (2-5 µg/ml). However, the optimal conditions should be determined individually.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified