Description
IL-18 (IFN-gamma-inducing factor, IGIF) is a novel proinflammatory cytokine that a?gments natural killer (NK) activity in spleen cells. It also has other biological properties such as activation of NF-kB, stimulation of Fas ligand expression, induction of CC and CXC chemokines. IL-18 increases production of competent HIV. IL-18 is related to the IL-1 family. One of the IL-18 receptor chains is the IL-1 receptor-related protein, a member of the IL-1R family. Like IL-1?, IL-18 is first synthesized as a leaderless precursor requiring the IL-1? converting enzyme (ICE) for cleavage into an active molecule. IL-18 may play a role in tissue injury in inflammatory reactions.
5180R | IL-18 Antibody DataSheet
Antibody Target: IL-18
Target Alternative Name: IL-18, IL18, IL 18, Interluekin-18, Interluekin 18, interluekin
Tag Line:
Category: Interluekin
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Mouse
Immunogen Sequence: Synthetic peptide of mouse IL-18
Accession #: P70380
Gene ID: 16173
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: 100 µg affinity purified rabbit anti-mouse IL-18 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.05% sodium azide.
Purification: Affinity purified
Application: Western blot, Immunoprecipitation, Neutralization
Positive Control:
Application And Usages: Western blot analysis (0.5-4 µg/ml), immunoprecipitation (2-5 µg/ml), and neutralization (2-5 µg/ml). However, the optimal conditions should be determined individually.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Size: |
100 ug |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |