IL-21, murine recombinant | 4183

Mouse Interleukin-21 (m-IL-21), expressed by activated CD4(+) T cells, is the newest member of the common gamma-chain family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-13. Its private receptor, IL-21R, is expressed on T, B, and NK cells. Within the B cell lineage, IL-21 regulates IgG1 production and cooperates with IL-4 for the production of multiple Ab classes in vivo. IL-21R has been shown to activate the Janus kinase/signal transducers and activators of transcription signaling pathways upon ligand binding. Initial studies have demonstrated that IL-21 has pleiotropic effects on the proliferation, the differentiation, and the effector functions of B, T, natural killer, and dendritic cells. Recombinant mouse IL-21, produced in E.coli, is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a total molecular mass of 15,095 Daltons.

4183 | IL-21 murine recombinant DataSheet

Biomolecule/Target: IL-21

Synonyms: IL-21, Interleukin 21

Alternates names:

Taglines: A cytokine regulating cells of the immune system

NCBI Gene ID #: N/A

NCBI Gene Symbol: N/A

Gene Source: N/A

Accession #: N/A

Recombinant: Yes

Source: N/A

Purity by SDS-PAGEs: 95%

Assay: RP-HPLC

Purity: 95%

Assay #2: HPLC

Endotoxin Level: <0.01 ng/g

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 8.934 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 20 mM NaHCO, pH 8.5

Reconstitution Instructions: Aqueous buffers, DMSO

Amino acid sequence: N/A