IL-25 Antibody [SB129a] | 99-796

IL-25 Antibody [SB129a] | 99-796 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: E. coli-expressed human IL-25

Research Area: Immunology

Tested Application: E, WB, IHC-P, IHC-WM, ICC

Application: IL-25 Antibody [SB129a] for use in ELISA assays.

Specificiy: IL-25

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [SB129a]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Interleukin-25, interleukin-17E, IL-17E

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Interleukin-25 (IL-25) , also known as interleukin-17E (IL-17E) , is a 17 kDa protein and member of the IL-17 cytokine family. This cytokine is secreted by a variety of cells including type 2 helper T cells (Th2) , bone marrow-derived mast cells, and alveolar macrophages. On target cells, IL-25 can induce the production of several type 2 cytokines including IL-4, IL-5, and IL-13 and implicates a role for this cytokine in type 2 immune response. Studies have linked this cytokine in promoting airway hyperreactivity, limiting pro-inflammatory cytokine production and chronic intestinal inflammation, and providing protective immunity following intestinal helminth infection.